Yes, circulation problems can affect results whether the sample is obtained from forearm or from fingerstick. Read the Owners' Manual for information on testing precautions and limitations. As stated in the package insert for OneTouch® Ultra® Meters, test results may be falsely low if you are severely dehydrated or severely hypotensive, in shock, or in hyperosmolar state (with or without ketosis). Critically ill patients should not be tested with blood glucose meters.